EAE相关论文
固有免疫（innate immunity）应答是机体抵抗外源性病原菌侵入以及清除体内自身抗原性异物的第一道防线。固有免疫应答针对的靶信号有......
Background: Src-Suppressed-C Kinase Substrate (SSeCKS) has been suggested as involved in regulating oligodendrocyte apop......
Epigenetic regulation of IL-12/IL-23 gene expression and autoimmune responses by deubiquitinase Trab
Aims: The proinflammatory cytokines IL-12 and IL-23 connect innate immunity to adaptive immune responses and are also in......
The major challenge for progressive multiple sclerosis therapy is the promotion of remyelination from inflammation-induc......
Long time Cola beverages consumption aggravates the pathogenesis of EAE through modulating intestina
Epidemiological evidence has linked dietary changes, which may greatly disturb the homeostasis between immune system and......
目的：探讨负性协同刺激分子B7-H4在C3H10T1/2细胞移植治疗小鼠EAE模型的体内效应机制。方法：利用MOG35-55和完全弗氏佐剂制备小鼠实......
CD226 ligation protects against EAE by promoting IL-10 expression via regulation of CD4+ T cell diff
IL-10 is an important anti-inflammatory cytokine that has been implicated in a variety of autoimmune conditions.Here we ......
N8-regulated entry of CD8+T cells into the CNS is required for the initiation of experimental autoim
Aim: In contrast to T cell priming in the periphery, therapeutic strategies targeting the initiation step of T cell traf......
Chronic treatment with caffeine attenuates inflammatory brain injury in experimental autoimmune ence
Caffeine,arguably the most widely consumed psychoactive drugs,has been recently shown to protection neuronal injury in a......
Activating cannabinoid receptor 2 alleviates pathogenesis of experimental autoimmune encephalomyelit
Aim Activation of cannabinoid receptor 2 (CB2R) has been reported to ameliorate the pathogenesis of experimental autoimm......
IFNγR expression on endothelial cells prevents brain inflammation by promoting blood-brain barrier f
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Retinoid-related orphan receptor gamma-t(RORγt)is a key regulator for the development and functions of Th17 cells which......
Multiple sclerosis(MS)is an autoimmune demyelination disease.IL-17–producing Th17 cells play a critical role in the dev......
Objective Multiple sclerosis(MS)is an inflammatory and neurodegenerative disease of the central nervous system that caus......
Autophagy mediates the protective effects of α7 nicotinic acetylcholine receptor aganist neuroinflam
Background and Purpose: α7 nicotinic acetylcholine receptor (α7nAChR) has been reported to alleviate neuroinflammation......
目的 观察补肾益髓胶囊(BSYS)对EAE小鼠MBP, MAP-2,Olig1及Olig2的表达影响,探索补肾益髓胶囊对EAE小鼠轴突及髓鞘损伤修复的影响.......
Aim:To observe the changes of the number of NKT cells in spleens and livers of induced model of experimental autoimmune ......
Role of a Novel C-type Lectin-like Inhibitory Receptor KLRL1 in Immune Tolerance and its Related Mec
KLRL1,which belongs to the killer cell lectin-like receptors (KLR),is encoded by the NK gene complex (NKC).Our previous ......
实验性过敏性脑脊髓炎（EAE）是多发性硬化（MS）的实验动物模型。髓磷脂碱性蛋白（MBP）免疫敏感动物诱导EAE的生物活性与分子内某些氨基酸顺......
目的了解自贡地区人群、动物源性食品、家禽及鸟类携带艾伯特埃希菌情况及菌株特征。方法采集市售牛肉、羊肉、猪肉、鸡肉、鸭肉、......
研究背景：多发性硬化(multiple sclerosis,MS)是一种慢性、炎症性、脱髓鞘的中枢神经系统疾病,在基础研究中我们常用实验性自身......
会议
目的观察黄芩茎叶总黄酮(Scutellaria baicalensisstem-leaf total flavonoids,SSTF)对实验性自身免疫性脑脊髓炎(experimental au......
为了探讨表没食子儿茶素没食子酸酯((-)-epigallocatechin-3-gallate,EGCG)治疗实验性自身免疫性脑脊髓炎(experimentalautoimmune......
目的观察骨髓间充质干细胞(BMSCs)治疗实验性自身免疫性脑脊髓炎(EAE)小鼠后血清中基质金属蛋白酶-9(MMP-9)的变化。方法实验随机......
目的:研究组织型纤溶酶原激活剂(t-PA)对实验性自身免疫性脑脊髓炎(EAE)小鼠病理性淋巴细胞与血脑屏障粘附的影响。方法:用MOG35-5......
目的:建立雌性Wistar大鼠实验性自身免疫性脑脊髓炎(experimental autoimmune encephalomyelitis,EAE)模型,观察银杏叶提取物EGb76......
FTY720, Sphingosine 1-Phosphate Receptor Modulator, Ameliorates Experimental Autoimmune Encephalomye
FTY720, a sphingosine 1-phosphate receptor modulator, induces a marked decrease in the number of peripheral blood lympho......
目的:探讨B细胞特异性衔接蛋白BANK(B cell adoptor protein with ankyrin repeats)在小鼠实验性自身免疫性脑脊髓炎(Experimental......
目的:通过拮抗剂阻断A1、P2Y1受体,测定神经胶质细胞源性神经营养因子(GDNF),研究益肾解毒通络法对EAE小鼠神经保护作用的机制,测......
目的:多发性硬化(multiple sclerosis,MS)是一种中枢神经系统(central nervous system,CNS)自身免疫介导的炎性退行性疾病,其病灶......
目的:多发性硬化症（Multiple sclerosis,MS）是一种常见的中枢神经系统疾病,目前大多研究认为它是一种T淋巴细胞功能异常的自身免疫性......
机体正常的免疫应答,是免疫细胞识别、淋巴细胞激活、免疫分子产生及免疫效应的一系列生理过程,而异常的免疫应答则造成组织病理性......
目的:多发性硬化(multiple sclerosis,MS)是一种引起中枢神经系统(central nervous system,CNS)发生非创伤性神经功能障碍的慢性疾......
目的探讨TNF-α及IL-8在实验性变态反应性脑脊髓炎(EAE)免疫学发病机理中的作用.方法自牛脑提取的髓鞘碱性蛋白(MBP)加福氏完全佐......
本文探讨了TNF-α及IL-8在实验性变态反应性脑脊髓炎(EAE)免疫学发病机理中的作用.方法：自牛脑提取的髓鞘碱性蛋白(MBP)加福氏完全......
目的：研究体液免疫在多发性硬化（ＭＳ）病程不同阶段中的作用。方法：采用Ｂｅｋｍａｎｎ免疫仪和ＭｏｎａｒｃｈＰｌｕｓ生化仪，对１０只食蟹猴中ＩｇＧ指数和ＩｇＧ合成率，进行实验性变态反应性脑脊......
凋亡是细胞的一种主动死亡形式,与神经系统自身免疫性疾病的发生、发展和转归密切相关。实验性自身免疫性脑脊髓炎(EAE)中凋亡的细......
